Berberine Powder Bulk – High-Purity Pharmaceutical Grade Ingredient

Berberine Powder Bulk

Shaanxi Nuoyuan Biotech Co., Ltd. supplies premium Berberine Powder Bulk with 98% purity, verified by HPLC testing. We are a professional company with over 10 years industry experience, a factory of 30,000 square meters, and the ability to handle 20,000 tonnes of raw materials each year. We use high quality Berberine Hydrochloride, a quaternary ammonium isoquinoline alkaloid derived from Phellodendron amurense and Coptis chinensis. This pharmaceutical grade ingredient provides constant lot to lot quality with optimised bulk density (0.45-0.65 g/ml) for smooth integration into your capsule, tablet and functional supplement manufacturing processes. We have stock on hand for immediate despatch to keep your supply chain flowing.

Certificate of Analysis (COA)

Product Name	Synthetic Berberine HCL	Batch number	/
Country of origin	China	Batch quantity	7000kgs

Analysis Item	Specification	Results
Appearance	Yellow crystal or crystalline powder	Yellow crystalline powder
Odor /Taste	Characteristic	Conforms
Impurity	None visible impurity	Conforms
Particle size	100% Pass 80 mesh	Conforms
Assay(on the anhydrous basis)	≥ 98%	98.3%
Loss on Drying	8.0% ~ 12.0%	11.3%
Residue on ignition	≤ 0.1%	0.1%
Heavy Metals	≤ 30ppm	< 30ppm
Lead (Pb)	< 1ppm	Not Detected
Arsenic (As)	< 1ppm	Not Detected
Cadmium (Cd)	< 1ppm	Not Detected
Mercury (Hg)	< 0.1ppm	0.034ppm
Sulphates	≤ 0.048%	< 0.048%
Acidity	The yellow color changes to an orange to red color	The yellow color changes to an orange
Total Plate Count	≤ 1000cfu/g	≤ 100cfu/g
Yeast and Mold	≤ 100cfu/g	≤ 10cfu/g
E.Coli.	Negative	Conforms
Salmonella	Negative	Conforms
Staphylococcus aureus	Negative	Conforms
Packing&Storage:	Packed in paper-drums and two plastic-bags inside; W:25kgs, I.D.35×H51cm; Store in a well-closed container away from moisture,light, oxygen.
Shelf life:	24 months under the conditions above and in its original packaging.

Manufacturing Process Excellence

We have processes for manufacturing medicinal quality products. We start with carefully chosen dried plant material from verified sources of Coptis chinensis and Phellodendron amurense.

Acidic leaching is the treatment of ground feedstock with regulated sulphuric acid solutions. This reaction transforms berberine into the soluble form for optimal yield. Then we add lime to the extract and make it alkaline to the proper pH.

Crude berberine is salted out effectively using sodium chloride. The crude product is then dissolved in hot water and acidified to pH 1-2 using strong HCl. Through regulated recrystallisation cycles we get pharmaceutical grade purity >98%.

5 HPLC testing units to evaluate the purity of each manufacturing step. This stringent technique removes all possible contaminants, but retains the bioactivity of the molecule.

Berberine Powder Bulk Key Benefits and Applications

Metabolic Health Support: Your consumers are looking for efficient blood sugar control solutions. Berberine turns on the so-called “metabolic master switch,” AMPK, in the body. This technique promotes insulin sensitivity and helps to naturally manage the blood glucose levels.

Cardiovascular health- The chemical lowers cholesterol and triglycerides via several mechanisms. It is useful in formulations for hyperlipidaemia control and beneficial for healthy lipid metabolism.

Anti-Inflammatory Effects: Berberine suppresses the secretion of pro-inflammatory cytokines such as TNF-α and IL-6. It is great for digestive health products and vascular protective formulae.

Antioxidant Protection: The chemical is a good scavenger of free radicals. It protects the cardiovascular, hepatic and renal organs against oxidative stress damage.

Antimicrobial Activity: Berberine disrupts bacterial cell membranes and produces reactive oxygen species. This wide range of activities supports goods for digestive health and gastrointestinal wellbeing.

Application Sectors: Your Berberine Powder Bulk is perfect for nutritional supplements, medicinal tablets, metabolic support capsules and traditional wellness formulations. For blood glucose management applications, normal formulation dosages are 900-1,500 mg/day.

Quality Certifications You Can Trust

ISO 9001 Quality Management System Certificate: Our facility operates under comprehensive quality management protocols. Each manufacturing batch is strictly tested from the raw material inspection to the final packing.

HALAL Certified: We adhere to stringent Islamic dietary standards. Your Muslim clients may confidently utilise goods with our ingredients.

STAR-K Kosher Certification: We produce in compliance with Jewish dietary requirements. With this accreditation, you open your business to the Kosher observant community.

FDA Registered: Our facility is registered with the FDA and is up-to-date. We observe Good Manufacturing Practices (GMP) at all phases of manufacturing.

Flexible Packaging Options

We understand different business needs require various package sizes:

25kg/fiber drum: Our primary commercial package for large-scale manufacturing operations
100g food-grade plastic and aluminium foil bag: Perfect for laboratory testing and quality evaluation
1kg food-grade plastic sacks and aluminium foil bag: Ideal for trial orders and small-batch formulation development
5kg food-grade plastic sacks and aluminium foil bag: Suited for medium-volume production runs
10kg food-grade plastic packs and aluminium foil bag: Designed for bulk trial orders before full-scale commitment

All packaging materials comply with international food safety requirements. We safeguard your goods against moisture, light and contamination in shipment.

Methods of Transportation

Fast Delivery: We deliver via DHL, FedEx, UPS, EMS, USPS etc. for orders less than 100kg. This enables fast delivery to your facilities, often within 5-7 business days.

Air Cargo: When time is of the essence with business shipments, air freight can make sure your bulk orders are delivered to their destination on time and without compromising product quality.

Sea Cargo: Cost efficient shipping for large commercial loads by sea. We provide container shipping with the correct papers for customs clearance.

All packing is in accordance with international shipping rules (IATA, IMDG standards etc.) Your merchandise will arrive safely, wherever it's going.

Warehouse & Shipping

Our Teams

Exhibitions

Frequently Asked Questions

Q : What is the minimum order quantity with you?

A: We may take sample requests from 100g for testing. Commercial orders are from 25kg each shipment.

Q: When can you ship once the order has been confirmed?

A: We have goods on hand. Most purchases ship within 3-5 business days following payment confirmation.

Q: Do you have any third party testing reports?

A: Yes, we provide COA with every batch. Third party testing is available from SGS or Eurofins upon request.

Q: What is the shelf life of your product?

A: Shelf life is 24 months from manufacture date when kept correctly (cold, dark, dry conditions).

Q: Do you offer OEM/ODM services?

A: Of course. We provide comprehensive customisation services, including formulation development, private label, and bespoke package design.

Q: How do you ensure consistent quality across batches?

A: Our 5 HPLC systems test every production batch. We have strong quality control measures throughout extraction, purification, and packing.

Contact Us

Ready to secure your Berberine Powder Bulk supply? Contact our team today at sales@nuoyuanbio.com for quotations, samples, and technical specifications.