Hydroxyapatite Powder Bulk

Hydroxyapatite Powder Bulk – Premium Biomimetic Mineral for Industrial Applications 

Shaanxi Nuoyuan Biotech Co., Ltd. delivers pharmaceutical-grade Hydroxyapatite Powder Bulk with a purity of 99% and precisely controlled particle sizes ranging from 20nm to 4.5μm. Our material has a proven Ca/P ratio of 1.67 guaranteeing high biocompatibility for medical, dental and cosmetic applications.

Our ISO 9001 certified 30,000㎡ factory, which can manufacture 20,000 tonnes per year, tests every batch using 5 HPLC systems to ensure consistent quality. Our product satisfies stringent international standards and comes in rod-and needle-shaped forms (40nm, 60nm, 200nm) and 20nm to 4.5μm in size. To assist you achieve your product development goals, we provide complete OEM/ODM customisation and maintain an inventory all year round to speed up delivery.

Certificate of Analysis (COA)

Key Benefits and Applications of Hydroxyapatite Powder Bulk

It is a bioactive product for many high value businesses. Its chemical structure is similar to that of natural bone and tooth enamel, which makes it a key ingredient in formulations needing good tissue integration.

The Oral Care Industry

Our substance is your choice for biomimetic remineralisation in toothpaste and mouthwash formulations. It's safe to swallow and offers a fluoride free option. It reinforces micro-cracks inside the enamel and lowers hypersensitivity. Its little abrasive action polishes without harming enamel surfaces.

Skin Care Advanced

In anti-aging treatments and sunscreens it increases collagen formation and acts as a physical filter, dispersing UV light. The soft-focus optical effect rapidly softens tiny lines, and the oil-absorbing capabilities keep a matte look going all day long.

Regenerative Medicine &

Our osteoconductive grades are used by orthopaedic surgeons and dental implant makers to promote bone integration. The material is stable to Gamma and EtO sterilisation and meets ASTM criteria for long term implantation.

Colour Cosmetics

The product is used as bulking and texturing ingredient in foundations, and pressed powders. The product enhances spreadability and provides a velvety skin feel. It stabilises emulsions and so increases the shelf life of products.

Manufacturing Process and Quality Control System

In our wet-chemical precipitation process, the orthophosphoric acid was mixed with calcium hydroxide at a regulated pH (>9) and temperature (25–90°C). The precipitate is aged, filtered and calcined at 800 to 1250°C to maximise its crystallinity.

Every manufacturing batch is subject to multi-stage inspection methods. Our quality team uses modern instruments to evaluate particle dispersion, surface area and trace contaminants. For situations where specialised morphologies are required, we also provide hydrothermal synthesis.

All shipments are fully traceable with batch records, stability data and regulatory compliance certifications included. We provide third-party testing services on request to satisfy your quality assurance needs.

Product Specifications & Customization

We understand that different applications demand precise particle engineering. Our Hydroxyapatite Powder Bulk catalog includes:

• Nano-grade (20–60nm): Ideal for cellular uptake studies and transdermal delivery systems
• Sub-micron (200nm): Optimized for cosmetic emulsions and transparent formulations
• Micron-grade (4.5μm): Perfect for mechanical polishing in dental prophylaxis products

Custom particle sizes, surface modifications, and Ca/P ratios are available through our OEM/ODM services. Our R&D team collaborates with you from concept to commercialization, adjusting specifications to match your formulation targets.

Sample amounts start at 100g and trial orders are available in 1kg and 5kg bundles. Minimum order for commercial use is 25kg per fibre drum for cost effectiveness of big scale manufacturing.

Standards & Certifications

Quality standards validated are key to your supply chain security. Shaanxi Nuoyuan Biotech is located at:

• ISO 9001 Quality Management System Certificate: Guarantees constant process control and continual improvement
• HALAL Certification: Verifies conformity with Islamic laws for food and material sources
• STAR-K Certification: Guarantees conformity to stringent standards of Kosher manufacture
• FDA Registered: We are registered with the U.S. Food and Drug Administration for export preparedness

The certifications help ensure our product fulfils worldwide regulatory standards, making it easier for you to prove compliance and accelerate time-to-market.

Packaging & Shipping Solutions

Standard Packaging Options:

Transportation Methods:

We arrange shipment via DHL, FedEx, UPS, EMS, or USPS for express delivery. Air cargo handles urgent commercial orders, while sea freight provides cost-effective solutions for large volumes. All packaging meets IATA and IMO international shipping standards. DDP air and sea options are available for hassle-free customs clearance.

Our logistics team coordinates with you to select the most efficient route based on your location and urgency requirements. Tracking information is provided immediately after dispatch.

Warehouse & Shipping

Our Teams

Exhibitions

FAQ

Q: What distinguishes your product from fluoride alternatives?

A：It has the same composition as natural enamel thus it can do real biomimetic restoration, not just surface coating. Great for kids oral care items with safety for ingestion.

Q: How do you verify the Ca/P ratio consistency?

A: Each batch is ICP spectroscopied to verify the 1.67 ratio, the signature of high purity hydroxyapatite that is equivalent to biological standards.

Q: Can the particle shape be modified for particular applications?

A: Yeah. We manufacture rod and needle shapes in size ranges from 20nm to 4.5μm, according to your functional needs.

Q: Is the material able to resist medical sterilisation procedures?

A: Yes. Gamma Radiation and Ethylene Oxide sterilisation are critical for implanted devices and our medical grade product is designed to withstand these sterilisation processes.

Q: What are your limits for heavy metals for safety?

A: Our standard is ASTM F1185, which limits the overall heavy metal level to less than 30 parts per million (ppm) to ensure long-term biocompatibility for medical applications.

Q: What is your minimum order quantity?

A：We accommodate sample orders starting at 100g for R&D purposes. Commercial MOQ is 25kg, with flexible scaling for growing businesses.

Contact Us

Ready to integrate premium Hydroxyapatite Powder Bulk into your formulations? Reach our technical sales team at sales@nuoyuanbio.com for quotations, samples, and customization inquiries.