Azelaic Acid Bulk Powder

Azelaic Acid Bulk Powder - Premium Quality Pharmaceutical & Cosmetic Grade

Shaanxi Nuoyuan Biotech Co., Ltd. supplies pharmaceutical-grade Azelaic Acid Bulk Powder with a guaranteed purity of ≥99% verified by GC testing. Our 30,000 square metre plant is ISO 9001 accredited and produces more than 20,000 tonnes of raw materials per year with 5 modern HPLC systems for rigorous quality control.

Our premium grade powder is defined by a melting point (106°C-110°C) and a micronised particle distribution (D90 < 20μm) to ensure no grittiness in formulations. This white to off-white crystalline powder is Certified by Halal and Kosher. CAS No. 123-99-9 Molecular formula C9H16O4

Flexible packaging from 100g test samples to 25kg industrial barrels. We have year round stock for quick shipping globe wide.

What is Azelaic Acid Bulk Powder?

The product is a natural dicarboxylic acid (C9H16O4) extracted from cereals such as barley and wheat, or synthesised by oxidation of oleic acid . This pharma-grade active ingredient has been acknowledged within the dermatological and cosmetic sectors for its ability to solve crucial skin issues.

The chemical is a multi-mechanism therapy for acne vulgaris, rosacea and post-inflammatory hyperpigmentation. Unlike antibiotic therapies, it is specific in its activity on hyperactive melanocytes and Propionibacterium acnes without adding to the problem of antimicrobial resistance.

It is chemically stable to oxidative stress and better than many sensitive actives. The powder is effective at pH 4.0-5.0, that is the natural acid mantle of the skin for maximum efficacy in professional formulas.

Certificate of Analysis (COA)

​​​​​​​Core Therapeutic Benefits

Your formulation challenges require reliable active ingredients. Our powder delivers measurable results through proven biological mechanisms.

Acne Management

It has keratolytic effect which helps clear pores and helps prevent germs from multiplying. The bacteriostatic action is directed at the bacteria responsible for acne, without affecting the good flora of the skin.

Anti-inflammatory effect

This inhibits inflammatory mediators that cause the redness and swelling associated with rosacea and sensitive skin diseases. Clinical trials reveal obvious calming benefits in 4-6 weeks.

Control of Pigmentation

Melanin production is inhibited by the enzyme tyrosinase. This process gently fades melasma, sun spots and post-acne lesions, but leaves natural pigmentation alone—making it a safer brightening choice than hydroquinone alternatives.

Antioxidant Defence

Antioxidant free radical scavenging properties protect compositions against oxidative degradation. This stability advantage enables it to be used with other active substances without impairing effectiveness.

Industrial Applications & Formulation Solutions

Professional formulators choose our micronized Azelaic Acid Bulk Powder for diverse applications across pharmaceutical and cosmetic sectors.

Prescription Dermatology

Acne vulgaris is often treated using medical-grade lotions and gels at a 15-20% concentration. We preserve pharmaceutical purity in accordance with high USP/EP standards for clinical goods.

Professional skin care lines

High performance serums, spot treatments and brightening solutions employ 8-15% concentrations. The micronised particle size gives a smooth feel and better skin penetration for leave-on products.

Combination Therapy

It is chemically stable at pH 4.5-5.0 and may be safely paired with niacinamide, hyaluronic acid, and peptides. It is not as quickly oxidised in multi-active formulas as retinol or vitamin C.

OEM/ODM Manufacturing

We provide complete customization services from formulation development to private-label packaging. Our technical team assists with solubility optimization using specialized polyol solvents to overcome the naturally low water solubility.

Manufacturing Excellence & Quality Assurance

Quality consistency begins with rigorous process control at every production stage.

Advanced Testing Infrastructure

Our quality lab operates 5 HPLC systems conducting real-time analysis. Every batch undergoes comprehensive testing including assay purity verification, impurity profiling, particle size distribution measurement, and microbiological screening.

Heavy Metal Control

ICP-MS testing ensures heavy metal content remains below 10 ppm, meeting international safety standards for cosmetic and pharmaceutical applications.

Micronization Technology

Specialized milling processes achieve uniform particle size distribution with D90 values consistently under 20 microns. This technical specification solves the common "gritty texture" problem reported with standard-grade powders.

Stability Testing

Accelerated stability studies confirm 24-36 month shelf life when stored below 25°C in light-resistant containers. Our material maintains assay values and prevents discoloration throughout its shelf life.

Certifications & Compliance

You need validated quality documentation for your supplier chain. We have complete certification portfolios that are recognised worldwide.

ISO 9001 Quality Management System 

We use globally recognised quality management processes to guide our production operations assuring traceability and continued product excellence.

HALAL Certified

Halal-certified, allowing market access to Muslim-majority markets in the Middle East, Southeast Asia and North Africa areas.

Kosher Certification by STAR-K

With rabbinical supervision to assure compliance with Jewish dietary laws, you may extend your business into North America and Europe.

FDA Registration

Our facility maintains FDA establishment registration, demonstrating commitment to US regulatory compliance and quality expectations.

Flexible Packaging & Global Logistics

We understand procurement flexibility matters for different business scales.

Package Options

packing: All packing is to international shipping standards with adequate sealing to ensure product integrity in transit.

Methods of Transportation

Express Shipping: DHL, FedEx, UPS, EMS for samples and small quantity, usually 3-7 days delivery.

Air Cargo. Perfect for business shipments that need quick replacement. Fast option for 50kg+ orders.

Sea Cargo: Ideal for big business shipments above 500kg, with flexible scheduling.

DDP Services: Door-to-door delivery via air or sea with customs clearance included, eliminating import complexity.

We maintain sufficient inventory enabling same-day dispatch for stock orders. Our logistics team provides real-time tracking information and professional export documentation support.

Warehouse & Shipping

Our Teams

Exhibitions

FAQ

Q: Why does the powder sometimes feel gritty in formulations?

A：The crystalline structure and low water solubility cause texture issues. Use our micronized grade (D90<20μm) or incorporate via specialized polyol solvents during the cooling phase.

Q: What is the optimum pH for stability and efficacy?

A: Keep formulation pH between 4.0-5.0 for optimal stability and biological activity, which matches the natural acid mantle of the skin.

Q: Will it work with other active substances?

A: Yes, it is chemically stable and may be used with niacinamide, hyaluronic acid and peptides without the worry of oxidation like retinol or vitamin C.

Q: What is the recommended storage condition?

A : Store below 25°C, in cool, dry, light resistant containers to avoid discolouration and to preserve shelf life of 24-36 months.

Q: What is your minimum order quantity?

A：We accommodate 100g samples for testing, 1kg trial orders for evaluation, and 25kg commercial MOQ for regular supply.

Q: Do you provide technical formulation support?

A：Our experienced team offers professional consultation throughout product development, from solubility optimization to stability testing guidance.

Contact Us

Ready to source premium Azelaic Acid Bulk Powder for your next formulation? Contact our sales team at sales@nuoyuanbio.com for quotations, samples, and technical support.