3-pyridinecarboxamide Powder
Description
Premium 3-Pyridinecarboxamide Powder – 99% HPLC Grade
Shaanxi Nuoyuan Biotech Co., Ltd. supplies premium 3-pyridinecarboxamide Powder at 99% HPLC-verified purity, produced in our ISO 9001 certified 30,000 square metre facility. We operate over 10 years of specialised expertise, processing 20,000 tonnes of raw materials every year with our modern manufacturing equipment.
CAS 98-92-0 Our product is of Pharmaceutical and Cosmeceutical grade quality. You benefit from our 5 HPLC testing methods that verify that each batch retains molecular integrity and eliminates the vasodilatory flushing impact associated with nicotinic acid. This white crystalline powder is very thermally stable and is suited for use in sophisticated production processes for applications in nutraceuticals, cosmetics and animal nutrition.

What is 3-Pyridinecarboxamide Powder?
Nicotinamide , commonly known as Niacinamide , is the bioactive amide of vitamin B3 . The product Unlike nicotinic acid, it is highly bioavailable without skin flushing.
The molecule is an important precursor for the coenzymes NAD (nicotinamide adenine dinucleotide) and NADP. These chemicals power cellular energy generation and metabolic repair throughout your body.
Our powder has the chemical formula C6H6N2O. In crystalline form, dissolving rates in water and lipid formulations may be uniform.
It is valued by pharmaceutical and cosmetic makers for its stability throughout a range of pH values. It may be included into emulsions, serums and tablets without any degradation problems.
Certificate of Analysis (COA)
|
Product Name |
Nicotinamide |
Batch Number |
/ |
|
|
Executive Standard |
USP2021 |
Batch Quantity |
4000kgs |
|
|
Analysis Item |
Unit |
Specification |
Test Method |
Result |
|
Appearance |
—— |
White, crystalline powder |
Eyeballing |
White crystalline powder |
|
Solubility |
—— |
Freely soluble in water and alcohol;soluble in glycerin |
Weight/volume method |
Conform |
|
Ultraviolet absorption * |
—— |
0.63-0.67(A245/A262) |
UV |
0.65 |
|
Infrared Identification * |
—— |
Conform to standard spectrum |
IR |
Conform |
|
Assay |
% |
98.5-101.5 |
HPLC |
99.1 |
|
Melting range |
℃ |
128-131 |
Melting point apparatus |
129.5-130.0 |
|
Readily carbonizable substances |
—— |
Not deeper than the Matching fluid A |
Colorimetry |
Conform |
|
Loss on Drying |
% |
≤0.5 |
Drying method |
0.02 |
|
Residue on ignition |
% |
≤0.1 |
Combustion method |
0.04 |
|
Mercury * |
ppm |
≤0.1 |
ICP-MS |
<0.01 |
|
Lead * |
ppm |
≤2.0 |
ICP-MS |
<0.05 |
|
Arsenic * |
ppm |
≤1.0 |
ICP-MS |
<0.01 |
|
Cadmium * |
ppm |
≤1.0 |
ICP-MS |
<0.01 |
|
Total Plate Count * |
cfu/g |
≤103 |
Plating |
<10 |
|
Yeast & Molds * |
cfu/g |
≤102 |
Plating |
<10 |
|
E. Coli * |
cfu/g |
Negative |
Plating |
Negative |
|
Salmonella * |
/25g |
Negative |
Plating |
Negative |
Conclusion: Complies with the requirements of USP2021.
Note: The items marked with * are for internal sampling inspection, in which the results of hazardous elements are from the external inspection report, and the results of other items are from internal inspection.
Core Advantages and Industrial Applications
Pharmaceutical Manufacturing
Our product may be used as a high purity substrate for synthesis of NAD+ precursors such NMN (Nicotinamide Mononucleotide). Purity 99.5% enables the highest efficiency of enzymatic conversion in your manufacturing process.
This chemical works against the metabolic defects that are linked to a deficiency of vitamin B3. It helps fuel the cell’s energy metabolism without unwanted vasodilatory side effects.
Cosmeceuticals Advanced
This powder is added at 2-5% levels by formulators for repairing weakened skin barriers. It stimulates ceramide formation in the stratum corneum, which lowers transepidermal water loss.
Controls sebum production to noticeably minimise pore appearance and manage excess shine. Its melanin transfer inhibitory capabilities efficiently erase hyperpigmentation, including post-inflammatory marks and photoaging spots.
Our powder is stable in complicated emulsion systems across the pH range 5.0-7.5. Your serums, moisturisers and nighttime treatments consistently function well.
Animal Nutrition Solutions
Livestock and aquaculture producers add this compound to premixes for preventing pellagra-like deficiency disorders. In high-stress intensive farming environments, it enhances growth rates and feed conversion ratios.
The powder's thermal stability withstands pelleting temperatures up to 85°C. Your manufacturing process benefits from uniform distribution in multi-component feed formulations.
Industrial Processing Excellence
We produce this compound through controlled chemical synthesis using nicotinic acid amidation. The reaction occurs at elevated temperatures (190-240°C) under precise pressure conditions with ammonia.
Our facility employs Raney nickel catalysts for the partial hydrolysis of 3-cyanopyridine. This method achieves up to 99% pure crystalline yield after multi-stage recrystallization.
The quality control of the incoming raw material starts with verification of the HPLC fingerprint. Each manufacturing lot is tested for related chemicals to assure that the nicotinic acid is <0.5%.
Loss on Drying (LOD) assays are performed to confirm moisture content is < 0.3%. Such close control minimises caking during storage, and provides constant flowability in automated filling equipment.
Particle size distribution testing guarantees uniform blending characteristics of 3-pyridinecarboxamide Powder. The 100-300 mesh range provides optimal dissolution rates for both immediate-release capsules and sustained-release matrix tablets.
Quality Management System Certifications
ISO 9001 Quality Management System
We work according to ISO 9001:2015 standards. This accreditation certifies our written methods for traceability of raw materials, quality inspections along the process and protocols for final product release.
HALAL Certification
Muslim-majority markets need food additives and dietary supplements to be HALAL certified. Our accreditation covers the whole production chain from sourcing to packaging.
Kosher Certification
STAR-K supervises our production line to maintain kosher standards. This certification opens distribution channels across North American and European markets where religious dietary compliance is essential.
FDA Registration
Manufacturing facility registered with the FDA. This registration means that ingredient suppliers to American pharmaceutical firms comply with Current Good Manufacturing Practices (cGMP).

Flexible Package Options for Every Order Scale
We offer five packaging configurations to match your procurement volume:
| Package Size | Package Type | Ideal For |
|---|---|---|
| 100g | Food-grade plastic + aluminum foil bag | Laboratory testing, formulation trials |
| 1kg | Food-grade plastic sack + aluminum foil bag | R&D development, small-batch production |
| 5kg | Food-grade plastic sack + aluminum foil bag | Medium-scale manufacturing runs |
| 10kg | Food-grade plastic pack + aluminum foil bag | Bulk trial orders before full commitment |
| 25kg | Fiber drum (primary commercial unit) | Regular production supply, inventory stocking |
All packaging materials comply with FDA food-contact regulations. The multi-layer aluminum foil barrier protects against moisture, oxygen, and light degradation during transit and storage.

Global Transportation Methods
Express Courier Services
For urgent samples and small orders less than 100kg, we ship via DHL, FedEx, UPS, EMS or USPS. North America typically receives deliveries between 5-7 business days, and European destinations within 6-9 days.
Air Freight Services
Air freight is used for business orders of medium volume (100-500kg). This is a good compromise between speed and affordability, taking between 7-12 days for delivery depending on the time needed for customs clearance at your destination airport.
Large Volume Ocean Freight
Bulk orders above 1,000kg are sent in 20′ or 40′ containers via maritime freight. Lead times for major ports in Europe and North America are 20-35 days.
Standards of Compliance
All bundling is in accordance with IATA requirements for air transportation and IMO standards for marine shipping. We supply full paperwork including MSDS, COA, packing lists and business invoices for easy customs clearance.

Warehouse & Shipping

Our Teams

Exhibitions

FAQ
Q: What is the minimum order quantity?
A: We have 100g samples available for test. Trial orders begin at 1kg, our normal commercial MOQ is 25kg per batch.
Q: How do you ensure consistent purity across batches?
A. Each manufacturing batch is tested using an HPLC assay. We save batch records for 3 years and can give COA comparative data on request.
Q: Can you customize specifications for pharmaceutical applications?
A: Sure. Our technical staff will modify the particle size distribution, residual solvent profile and microbiological limitations to fit your unique pharmacopeia needs.
Q: How long does it last if stored correctly?
A: The powder is 99%+ pure and is stable for 36 months when kept in its original unopened package at room temperature (15-25°C) away from moisture.
Q: Do you provide OEM formulation services?
A: Our R&D section formulates unique mixes, pills, capsules and softgels. From idea to market, we develop formulation, conduct stability testing and provide private-label packaging.
Q: Do you provide third party lab testing?
A. We organise testing with SGS, Eurofins or other recognised labs. Costs and lead times depend on the analytical panel you want.
Contact Us
Ready to source pharmaceutical-grade 3-pyridinecarboxamide Powder with guaranteed purity? Contact our technical sales team for quotations, COA samples, and customized solutions: sales@nuoyuanbio.com
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