Papain Powder Bulk
Description
Papain Powder Bulk – Premium Proteolytic Enzyme from Shaanxi Nuoyuan Biotech
Shaanxi Nuoyuan Biotech supplies premium Papain Powder Bulk extracted from the unripe fruit of Carica papaya, made at our 30.000 square meters ISO certified factory with an annual processing capacity of 20.000 tonnes. Our enzyme powder provides high activity (50,000 U/g to 200,000 U/g) and batch-to-batch consistency for your industrial demands.
The product is a proteolytic enzyme that hydrolyses peptide links in proteins to smaller peptides and amino acids. This makes it suitable for applications that need dependable enzymatic stability throughout long distance logistics and accurate dose control in big scale production.
The product is most stable between pH 5.0 and pH 8.5 and stays active up to a temperature of 70°C. We have 5 HPLC testing equipment to regulate quality strictly. We ensure that every batch fulfils worldwide food safety and pharmaceutical requirements.

Certificate of Analysis (COA)
|
Product Name |
Papain |
Batch number |
/ |
|
Part Plant |
Papaya |
Batch quantity |
6500kgs |
|
Quality |
Food Grade |
Country of origin |
China |
|
Analysis Item |
Specification |
Result |
|
Appearance |
Off white powder |
Visual |
|
Odor |
Free of offensive odours |
Smell |
|
Impurity |
None visible impurity |
Visual |
|
Activity of enzyme |
600,000 u/g |
603,200 u/g |
|
Loss on Drying |
≤5.0% |
3.20% |
|
Loss on ignition |
≤5.0% |
3.50% |
|
Heavy Metals |
≤30mg/kg |
<2.0mg/kg |
|
Lead (Pb) |
≤2.0mg/kg |
<2.0mg/kg |
|
Arsenic (As) |
≤2.0mg/kg |
<30mg/kg |
|
Cadmium (Cd) |
≤1.0mg/kg |
<1.0mg/kg |
|
Mercury (Hg) |
≤1.5mg/kg |
<1.5mg/kg |
|
Total Plate Count |
<10,000cfu/g |
2,600cfu/g |
|
Yeast and Mold |
NMT 100cfu/g |
Conforms |
|
Coliforms |
<30cfu/g |
<30cfu/g |
|
Salmonella |
Negative/25g |
Conforms |
|
Staphylococcus aureus |
Negative |
Conforms |
|
Storage: |
Stored humidity protected (RH less than 60) at temperature below 4℃ |
|
|
Shelf life: |
12 months under the conditions above and in its original packaging. |
|
Industrial Applications & Solutions of Papain Powder Bulk

When you source goods from Nuoyuan Biotech, you're receiving more than an enzyme, you're getting actual solutions to production difficulties.
Excellence in Food Processing
Broad substrate specificity of our papain enhances your meat tenderisation processes. It breaks down stiff protein fibres in beef, pig and poultry in minutes. Breweries depend on our product for chill-proofing and clarifying beer without affecting flavour qualities.
Pharmaceutical & Nutraceutical Production
Formulators add our enzyme to digestive health supplements and systemic enzyme treatment solutions. On the tablet and capsule production processes, the powder mixes easily with excipients. Its bioactivity is retained via compression and coating techniques.
Development of the cosmetic products
Your skin care products receive effective exfoliating power. This enzyme gently digests dead keratinocytes, making it much preferable than harsh chemical peels. It is stable in surfactant-heavy cleansers and emulsion-based masks, where many synthetics break down.
Dietary Supplement Innovation
Health-conscious people look for natural digestion remedies. Our product helps alleviate bloating and assists with protein absorption, while also meeting the rising need for plant-based health products.
Manufacturing Process & Quality Control
We manufacture to rigorous pharmaceutical standards to ensure reproducible quality.
Selection of Raw Material
We get latex from selected papaya farms guaranteeing the best enzyme concentration. The milky latex is gathered from the unripe fruit at its full maturity.
Precise Extraction
Then we coagulate and filter and then precipitate in a regulated manner using food grade ethanol. Centrifugation separates the enzyme paste to remove any contaminants that might damage your final result.
Drying with Stability Preservation
Low temperature vacuum drying (<60℃) inhibits enzyme denaturation. This is a key stage and the reason why our Papain Powder Bulk is at greater levels of activity than rivals that use standard spray drying.
Testing & Standardisation
Each batch is activity tested on our 5 HPLC systems. Each lot is standardised to your specific enzyme units, so you don't have to worry about the unpredictability that disturbs production plans. Microbial testing, heavy metal screening and residual solvent analysis assure worldwide regulatory compliance.
Technical features & Competitive advantages
Get the scoop on the science of papain to help you optimise formulations.
The Efficiency of Enzymes
Our enzyme, a cysteine protease of 212 amino acid residues, has a very good catalytic efficiency. It hydrolyses animal and plant proteins, offering you formulation flexibility that single-substrate enzymes do not provide.
Robustness to the environment
Your manufacturing environment is not consistent, there are temperature swings, variations in pH and mixing shear forces are a reality. Our papain is tolerant to such circumstances, sustaining activity between pH 3-10 and resisting heat stress up to 70C when substrate-stabilized.
Solubility & Handling
It is highly soluble in water and in glycerol based solutions. This makes it easier to incorporate into liquid compositions and decreases processing time in your blending processes.
Regulatory Compliances
We are compliant with USP, FCC and ISO 22000. Open new markets that need religious compliance with HALAL and KOSHER certifications and increase distribution possibilities.
Quality Certifications

Our dedication to excellence is certified by globally recognised certifications:
ISO 9001 Quality Management System Certificate
Shows how we monitor quality systematically - from the purchase of raw materials to the final packaging.
HALAL CERTIFIED
Guarantees adherence to Islamic dietary regulations, a necessity for markets in the Middle East, Southeast Asia, and Muslim populations throughout.
STAR-K Kosher Certificiation
Ensures compliance with Jewish dietary laws, creating potential in North American and European markets with kosher-observant populations.
FDA Registration
Our facility is registered with the U.S. Food and Drug Administration, providing additional assurance of manufacturing standards and traceability.
Flexible Packaging Options

We understand different order volumes require different packaging solutions:
| Package Size | Packaging Type | Ideal For |
|---|---|---|
| 100g | Food-grade plastic + aluminum foil bag | Testing & sampling |
| 1kg | Food-grade plastic + aluminum foil bag | Trial orders & R&D |
| 5kg | Food-grade plastic + aluminum foil bag | Medium quantities |
| 10kg | Food-grade plastic + aluminum foil bag | Bulk trial orders |
| 25kg | Fiber drum (standard commercial) | Regular production supply |
All packaging meets international shipping standards and protects enzyme activity during transit.
Global Transportation Methods

Your shipment reaches you safely, regardless of location or order size:
Express Courier Services
Sample orders and urgent replenishment via DHL, FedEx, UPS, EMS, USPS. Standard delivery is 5-7 business days to major cities around the globe.
Commercial Orders Air Cargo
Perfect for items >100kg that need a quicker arrival than sea freight. Temperature regulation strategies to ensure enzyme stability.
Sea Cargo High Volume
Low cost option for container loads (500kg+). Our logistics staff takes care of the papers, the customs processing and the door to door delivery.
DDP Air & Sea Choices
Delivered Duty Paid service eliminates customs hassles. All import fees and taxes are paid when you receive items at your location.
All bundling is GMP compliant and complies with international shipping rules for simple customs clearance.
Warehouse & Shipping

Our Teams

Exhibitions

Frequently Asked Questions
Q: What is your enzyme activity level?
A: We provide standardised activities from 50,000 U/g to 200,000 U/g; Custom activity specification is available for orders above 500kg.
Q: How stable is the enzyme during shipping?
A: When kept in our sealed packaging at room temperature for 12 months, activity stays over 95%. We prefer air freight for tropical locations.
Q: Can you provide samples before bulk ordering?
A: Yes, we offer 100g test samples. For sample requests and technical data sheets contact sales@nuoyuanbio.com.
Q. What documents do you provide?
A: Each shipment is accompanied by COA, MSDS, Allergen statement, BSE/TSE declaration and certifications (ISO, HALAL, KOSHER). Further material available on request.
Q: What is your MOQ?
A: Sample order begins at 100g. Commercial MOQ is 25Kg . We have available stock for immediate delivery.
Q: Do you provide formulation technical support?
A: As you create your product our technical staff will work with you on enzyme loading, pH optimisation and stability testing.
Contact Us
Ready to source reliable Papain Powder Bulk for your manufacturing needs? Reach out to our team at sales@nuoyuanbio.com for quotes, samples, and technical specifications.
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