Alpha- Ketoglutaric Acid Powder

Alpha- Ketoglutaric Acid Powder – High-Purity Metabolic Intermediate

Shaanxi Nuoyuan Biotech Co., Ltd. delivers pharmaceutical-grade Alpha- Ketoglutaric Acid Powder at 99% purity, backed by over 15 years of specialized manufacturing experience. Our product is processed in our ISO 9001 certified 30,000㎡ plant with a 20,000 tonne annual capacity , and fulfils USP and Ph.Eur requirements with heavy metal levels below 3ppm (Pb) and 1ppm (As).

We do thorough HPLC testing on each batch with our 5 modern analytical equipment, therefore we can guarantee moisture content below 0.5% and pH range of 1.5-2.5 in aqueous solution. We provide a product (CAS 328-50-7, Molecular Formula C5H6O5) that has enhanced heat stability and water solubility, suitable for nutraceuticals, sports nutrition, and therapeutic applications. We assure you of the best quality for your business requirements, rapid stock availability and complete Halal and Kosher certification.

What Is Alpha- Ketoglutaric Acid Powder?

It is a white crystalline molecule and an important step in the tricarboxylic acid (TCA) cycle, the powerhouse of the cell. This naturally occurring chemical powers creation of ATP, the major fuel source for your body’s cells.

In addition to its role in energy metabolism, it acts as a nitrogen scavenger reducing ammonia accumulation while stimulating glutamate and glutamine production. These amino acids are important in muscle protein synthesis and in the prevention of muscle catabolism under physical stress.

The powder form has unique benefits such accurate dosing for custom-made formulations, fast bioavailability and very good stability under normal processing conditions. Stored under correct conditions of low humidity it will hold for long durations.

Certificate of Analysis (COA)

Core Benefits and Applications

Sports Nutrition & Performance

Optimised protein synthesis = muscles get a harder workout. This solution helps you to prevent muscle breakdown during rigorous exercise and speeds up recovery after your workout. It’s a common element in pre-workout mixes and recovery products when endurance is important.

Cellular Energy and Metabolism

It is a direct contributor to ATP production, the currency your cells employ for every metabolic operation. It is an intermediary in the TCA cycle. This makes it beneficial to anybody looking for metabolic optimisation or cellular vitality support.

Clinical & Therapeutic Use 

It is used by healthcare personnel to help patients with chronic renal diseases, since it regulates nitrogen metabolism. It's protein sparing properties are especially beneficial for post-surgical recovery programs.

Anti-Aging & Longevity Research 

Recent research are investigating its ability to reduce DNA methylation age via epigenetic control. This makes Alpha- Ketoglutaric Acid Powder a suitable choice for supplement research focusing on lifespan.

Antioxidant and Immune System Support

It serves as a cellular antioxidant, neutralising free radicals and aiding immune cell activity. This dual action serves to bolster cellular health and resilience overall.

Process Excellence in Production

Our process includes innovative microbial fermentation technology employing modified strains such as Corynebacterium glutamicum. This green process turns renewable glucose sources into high yield AKG with low environmental effect.

Stringent process controls are in place to maintain the substrate concentration, pH and temperature parameters during fermentation. Multi-stage purification eliminates contaminants. Crystallisation gives consistent particle size.

Our quality checks at each step from the verification of the raw material to final packaging ensure batch to batch consistency. Our 5 HPLC systems provide real time analytical data so no inferior material ever reaches your facility.

Quality Certifications You Can Trust 

ISO 9001 Quality Management System

We have a broad set of quality procedures that encompass the whole process from qualifying suppliers to closing the loop with our customers.” Frequent audits ensure adherence to international standards.

HALAL Certification 

All manufacturing methods are in accordance with Islamic dietary regulations recognised by authorised bodies. This confirms that our ingredient is suitable for usage by your Muslim consumers.

STAR-K Kosher Certification 

Rabbinical oversight assures stringent kosher compliance, unlocking markets where religious dietary observation is important.

Registration with FDA

Our facility is registered with the U.S. Food and Drug Administration, showing our dedication to safety and regulatory compliance for the American markets.

Flexible Packaging Options

We understand different project scales require different packaging solutions:

• 100g food-grade bags – Perfect when you're testing formulations or conducting stability studies
• 1kg aluminum foil bags – Ideal for pilot batches and initial market trials
• 5kg multi-layer bags – Medium-scale production runs get cost efficiency without excess inventory
• 10kg bulk packages – Pre-commercial volumes at optimized pricing
• 25kg fiber drums – Our standard commercial unit for established production schedules

All packaging materials meet international shipping standards and protect against moisture, light, and contamination. Inner aluminum foil layers provide additional barrier protection.

Global Transportation Solutions

Express Shipping

DHL, FedEx, UPS, EMS, and USPS options deliver samples and small orders to your door within 3–7 days. Door-to-door tracking keeps you informed throughout transit.

Air Cargo

For orders between 100kg and 500kg, air freight balances speed and cost. Typical delivery times range from 5–10 days to major international airports.

Sea Freight

Bulk commercial shipments above 500kg benefit from ocean transport's cost advantages. Container loads arrive in 20–40 days depending on destination port.

DDP Services

Delivered Duty Paid options (by air or sea) make customs clearance easier. We take care of the paperwork, duties and taxes, so your cargo is ready to go.

Each shipment is accompanied with the relevant paperwork (commercial invoices, certificates of analysis, MSDS sheets, and any import permissions needed for your country).

Warehouse & Shipping

Our Teams

Exhibitions

FAQ

Q : How many do you order at a time?

A: We accept sample requests from 100g and above. Trial orders start at 1kg and commercial orders start at 25kg per batch.

Q: How do you maintain constant purity from batch to batch?

A: Every batch is analysed by HPLC at three points: after fermentation, after purification and before packing. Certificates for every shipment.

Q: Do you make bespoke specs?

A: Yeah. Our technical staff can customise blends, particle size or moisture content to suit your formulation needs.

Q: What is the shelf life of your powder?

A: If kept in the original packaging at room temperature (below 25 °C) and humidity less than 60 %, shelf life is 24 months.

Q: Do you provide regulatory support documents?

A: Yes, certainly. Upon request, we may provide COAs, allergy statements, BSE/TSE declarations, non-GMO certifications, and kosher/halal paperwork.

Q: What are your conditions of payment?

A: T/T, Paypal, Western Union all available. Existing clients are welcome with flexible payment options subject to credit assessment.

Contact Us

Ready to source premium Alpha- Ketoglutaric Acid Powder for your next formulation? Reach our technical sales team at sales@nuoyuanbio.com for quotations, samples, or technical specifications.