α-Arbutin Powder

α-Arbutin Powder – Premium Skin Brightening Active Ingredient

Shaanxi Nuoyuan Biotech Co., Ltd. delivers pharmaceutical-grade α-Arbutin Powder at 99% purity, produced in our ISO 9001 certified facility of 30,000 square meters. We have 15 years of OEM/ODM experience, and an annual processing capacity of 20,000 tonnes, which can provide reliable supply and outstanding quality. Our product (CAS 84380-01-8) has a particular optical rotation from +174.0° to +184.0° which is the specific rotation for the legitimate alpha-isomer structure and is 10 times more efficient in tyrosinase inhibition than beta-arbutin. Rigorous testing on 5 HPLC systems assures hydroquinone residual below 10ppm, satisfying EU and FDA safety guidelines for global cosmetic use.

What Is α-Arbutin Powder? 

It is a biosynthetic, water soluble molecule. The scientific name is 4-Hydroxyphenyl-α-D-glucopyranoside. This premium component is different from regular beta-arbutin in that it is enzymatically generated by bonding glucose to hydroquinone in an alpha-linkage structure.

This new sophisticated structure provides improved stability and effectiveness. It is a powerful tyrosinase inhibitor, stopping melanin production at the source, without the cytotoxic dangers of hydroquinone, which is prohibited in many places.

The solution answers three big difficulties for formulators and brands: a safer alternative to lightening, outstanding stability in water-based systems and noticeable effects for hyperpigmentation, melasma and dark spots.

Certificate of Analysis (COA)

Key Benefits and Applications

α-Arbutin Powder is your go-to ingredient for high-performance brightening formulations.

Core Benefits:

• Inhibits Tyrosinase Activity: Competitively inhibits melanin formation, erasing dark patches, melasma and post-inflammatory hyperpigmentation.
• Superior Stability : Stable at pH 4.0-6.5, heat stable up to 100°C . Ideal for a wide range of cosmetic bases .
• Safe & Gentle Non-cytotoxic, for delicate skin, unlike hydroquinone.
• Synergistic Power: Works synergistically with niacinamide, vitamin C and kojic acid to enhance the brightening benefits.

Applications: 

It may be added to serums, lotions, creams, toners, and sheet masks. Normal use amounts are 0.5% to 2% in leave-on cosmetics.

Long-term stability testing showed no substantial deterioration over 16 months, giving you confidence that your formulas will work from the factory floor to the consumer’s hands.

Why Choose Our α-Arbutin Powder?

1. Excellence in Biosynthetic Production

We use enhanced enzymatic synthesis employing sucrose phosphorylase and hydroquinone substrates under moderate circumstances. Controlled procedure results in high purity α-isomer with few contaminants.

After synthesis, our product undergoes macroporous resin chromatography purification followed by rotary evaporation, achieving pharmaceutical-grade purity exceeding 99%.

2. Rigorous Quality Control

Our quality team operates 5 HPLC testing systems, monitoring every production batch. We verify specific rotation to prevent cheaper beta-arbutin contamination and strictly control hydroquinone residue to meet international safety standards.

Tests for heavy metals, microbiological counts and moisture content as per USP procedures. With every shipment we check the Certificate of Analysis.

3. Manufacturability and Scalability

We have 20,000 tonnes yearly processing capacity and support trial orders from 100g to commercial levels above 1,000 kg. With enough inventory, you have fast turnarounds and reliable supply chains for your product launches.

Certifications & Compliance

Your α-Arbutin Powder formulations deserve ingredients backed by global standards.

• ISO 9001 Quality Management System: Ensures consistent manufacturing processes and traceability.
• HALAL Certification: Meets Islamic dietary and ethical requirements for Muslim-majority markets.
• STAR-K Kosher Certification: Complies with Jewish dietary laws, expanding your market reach.
• FDA Registration: Our facility is registered, supporting your regulatory submissions.

Third-party testing services are available upon request for additional verification.

Flexible Packaging Options

We offer packaging solutions tailored to your order size:

All packaging meets international shipping standards, protecting your product from moisture, light, and contamination.

Transportation & Delivery

Express Shipping:

For small orders and urgent needs, we ship via DHL, FedEx, UPS, EMS, and USPS. Typical delivery time is 3–7 business days to North America and Europe.

Air Cargo:

Ideal for medium-volume commercial shipments requiring faster delivery than sea freight.

Sea Cargo:

Economical method for bulk and contractual delivery.

We have inventory year-round so can respond quickly and shorten lead times. We provide DDP air and DDP marine alternatives, making it easy for you to cross customs.

Warehouse & Shipping

Our Teams

Exhibitions

FAQ 

Q: Why is α-Arbutin superior than β-Arbutin?

A: Alpha-arbutin has an alpha linkage which is 10 times more potent in tyrosinase inhibition. It also hydrolyses better and maintains potency throughout the product’s shelf life.

Q: Is it appropriate for delicate skin formulations?

A: Yes. We don't use parabens, sulphates or artificial perfumes in our product. It is non-cytotoxic and highly tolerated, making it perfect for delicate skin lines.

Q: What do you do with hydroquinone residue?

A: We use verified HPLC procedures to verify hydroquinone is below 10ppm which is in accordance with EU and FDA safety rules for cosmetic usage.

Q: Can I get bespoke packaging or private labelling?

A: Absolutely. We provide complete OEM/ODM services including bespoke formulas, package design and private label to assist you in building your brand.

Q: What's the minimum order quantity?

A: We have 100g test kits for sampling. Commercial orders start at 25kg, although smaller trial amounts (1kg, 5kg, 10kg) are also available.

Q: How long does α-Arbutin remain stable in formulations?

A：When stored properly at pH 4.0–6.5, our testing shows no significant degradation over 16 months in finished products.

Contact Us

Ready to elevate your α-Arbutin Powder brightening formulations? Reach out to our team at sales@nuoyuanbio.com for COA, samples, or technical support today.