L-threonine Bulk Powder

L-threonine Bulk Powder – High-Purity Essential Amino Acid for Feed & Nutrition

Shaanxi Nuoyuan Biotech Co., Ltd. delivers premium L-threonine Bulk Powder with a guaranteed purity of ≥98.5%, created by sophisticated microbial fermentation and evaluated across 5 HPLC systems. Our facility is 30,000 square meters and the processing capacity is 20,000 tonnes per year, assuring constant supply and consistent quality.

Our expertise spans more than 15 years in the OEM/ODM industry. Under the auspices of the USP, AJI, and EP, we manufacture L-threonine of medicinal and feed grades. The proper functioning of the immune system, the digestive tract, and protein synthesis all depend on this crucial amino acid. Whether you're working on therapeutic nutrition solutions or animal feeds, our product provides reliable bioavailability and thermal stability, even when pelleted at high temperatures.

What is L-threonine Bulk Powder?

The human body is unable to produce the essential alpha-amino acid L-threonine. Either eating certain foods or taking a supplement will provide it to you.

The fermentation of carbohydrates, such glucose or maize starch, yields a crystalline substance that is white to off-white in colour and finds use in industrial settings. It weighs 119.12 molecularly and has the chemical formula C₄H₋NO₃.

This amino acid is very important for the production of proteins. It is a building block of structural proteins, enzymes and antibodies. It is the second or third limiting amino acid in corn-soybean meal diets in animal nutrition.

Threonine powder of high purity may be used to improve feed compositions. This minimises the dependency on costly crude protein sources, while preserving growth performance and minimising nitrogen emissions.

Certificate of Analysis (COA)

Key Benefits and Applications

For Animal Feed

Supplementation of swine and poultry diets with L-threonine may markedly enhance feed efficiency. Amino acid profile balancing allows you to drop crude protein 1-2% without losing growth rates.

This amino acid improves the integrity of the intestinal mucosa. It increases mucin synthesis, a protective coating in the stomach. The young animals gain the most, particularly during the weaning stress periods.

Threonine also assists the immune system. It's a precursor to immunoglobulins and T cell activity. Healthier animals equals less antibiotics and greater welfare standards.

For Clinical Nutrition 

Threonine in parenteral and enteral formulae sustains nitrogen equilibrium throughout recovery. Malnourished and post-surgical patients need certain amino acid ratios. Our pharmaceutical-grade powder satisfies those exacting standards.

For Fortified Food and Nutraceuticals

Plant-based protein products often have low levels of threonine. You may strengthen them to match the amino acid profile of animal proteins or human milk. This is crucial for newborn formulae and vegan supplements with a focus on comprehensive nutrition.

Production Process: Fermentation to Crystallization

We manufacture L-threonine Bulk Powder from metabolically engineered strains of Escherichia coli. Under fermentation control these microbes convert glucose into threonine.

The method starts with inoculation in sterile medium. After 48–72 h the soup is high in L-threonine. Microbial cells are then separated by microfiltration and the fluid concentrated by ultrafiltration.

The purified solution is cooled and the pH is adjusted, resulting in crystallisation. The thus obtained crystals are cleaned, dried and ground to a fine powder. This procedure guarantees a constant purity, a low content of by-products and a high repeatability batch after batch.

Our facility complies with ISO 9001. Bioburden, residual solvents and trace pollutants are evaluated during each manufacturing cycle.

Technical Characteristics

L-threonine is quite soluble in water, about 90 g/L at 20°C. This makes it simple to add to liquid pre-mixes or spray dried formulations.

One of its chief advantages is its heat stability. The bioavailability is not influenced during feed pelleting at temperatures up to 85°C. But exposure to temperatures over 150°C in the presence of reducing sugars might generate Maillard reactions that may marginally reduce effectiveness.

Optical purity was determined by specific rotation in the region from -26.0° to -29.0°. Moisture content must be below 1.0% for extended shelf life and to avoid caking during storage.

This amino acid may be relied on to function reliably in a wide variety of processing conditions from high-shear mixers to extrusion lines.

Certifications

Compliance and traceability drive your sourcing choices. Our Certifications are as follows:

ISO 9001 Quality Management System Certificate. Provides strict process control and continual improvement.

HALAL Certification : Appropriate for Islamic dietary-compliant markets.

STAR-K Kosher Certification: Inspected for Kosher Production Standards.

FDA Registration: Our facility is registered with the U.S. Food and Drug Administration for Export Readiness.

Serving regulated sectors or a varied client base, these credentials might help give you assurance that your product is sound.

Package Options

We offer flexible packaging to suit trial orders, medium-scale production, and bulk commercial shipments:

• 100g food-grade plastic and aluminium foil bag: Ideal for laboratory testing and sample evaluation.
• 1kg food-grade plastic sacks and aluminium foil bag: Perfect for trial formulations and R&D projects.
• 5kg food-grade plastic sacks and aluminium foil bag: Suitable for pilot production runs.
• 10kg food-grade plastic packs and aluminium foil bag: Designed for bulk trial orders and regional distributors.
• 25kg fiber drum: The primary commercial package for large-scale manufacturing and long-term inventory.

All packaging materials comply with international shipping standards. They protect the product from moisture, light, and contamination during transit.

Transportation Methods

We understand that timely delivery matters. That's why we offer multiple shipping solutions:

• Express Courier (DHL, FedEx, UPS, EMS, USPS): Fast delivery for samples and small orders, typically 3–7 business days.
• Air Cargo: Cost-effective for moderate to large commercial shipments, usually 5–10 days.
• Sea Cargo: Economical for bulk orders exceeding 500 kg, with lead times of 20–35 days depending on destination.

All shipments are backed by adequate documentation: Commercial Invoice, Packing List, Certificate of Analysis and Health Certificate (where applicable). We also provide DDP (Delivered Duty Paid) solutions for easy customs clearance.

Warehouse & Shipping 

Our Teams

Exhibitions

FAQ 

Q: Why do gut health-focused diets need threonine?

A: It is the main amino acid for mucin production, which is the protective coating of mucus in the stomach.

Q: How does heat during pelleting affect the powder?

A: L-threonine is stable up to 85 °C. High temperature (>150°C) may modestly diminish bioavailability via Maillard process.

Q: Can soybean meal be replaced with threonine in feed?

A: It permits a 1-2% reduction in crude protein, fills the threonine gap, reduces nitrogen emissions and does not impact growth.

Q: What is the shelf life?

A: It will typically last 24 months if kept in a cool, dry, well-ventilated place in the original sealed container.

Q: What is the difference between Feed Grade and Food Grade?

A: Food Grade has more thorough testing for heavy metals, and more restrictive limits for microbes.

Q: Do you do bespoke formulations?

A: Yes. We provide OEM/ODM services for bespoke mixes, capsules, tablets, and private label.

Contact Us

Ready to optimize your formulations with high-purity L-threonine Bulk Powder? Reach out to our team today: sales8@nuoyuanbio.com