Premium Gaba γ-Amino Butyric Acid Powder – Pharmaceutical-Grade Neurotransmitter Supplement

Shaanxi Nuoyuan Biotech Co., Ltd. produces pharmaceutical-grade Gaba γ-Amino Butyric Acid Powder with verified purity ≥99% (HPLC tested). Our production site is ISO 9001 accredited and covers an area of 30,000㎡. We handle over 20,000 tonnes of raw materials every year and manufacture using innovative microbial fermentation. Our product is CAS No 56-12-2 with molecular formula of C₄H₉NO₂ with great water solubility of 130g/100mL (25°C) and thermal stability up to 204°C, which is suitable for capsule, beverage and functional food. We are certified Halal and Kosher, we stock all year round and ship worldwide in 5-7 days by DHL/FedEx.

What Is Gaba γ-Amino Butyric Acid Powder?

It is a naturally occurring non-protein amino acid and the major inhibitory neurotransmitter in the brain. It is produced by enzymatic decarboxylation of Lglutamic acid using high efficiency fermentation bacteria such as Lactobacillus hilgardii .

Compared to manufactured chemicals, our fermentation powder has better bioactivity. It meets important market needs for non-pharmacological stress treatment, sleep optimisation and cardiovascular support. The powder has low molecular weight (103.12 g/mol) that can be absorbed efficiently via the gut-brain axis.

Manufacturers prize this component because it helps address formulation issues in mood-support supplements and functional drinks. It may be integrated seamlessly into various product matrices without impacting sensory quality due to a neutral taste profile and obvious dissolving characteristics.

γ-Amino Butyric Acid Powder

Physical and Chemical Properties

Our product demonstrates superior technical specifications for industrial applications:

Property	Value	Testing Method
Appearance	White to off-white crystalline powder	Visual inspection
Assay (Purity)	≥99.0%	HPLC
Molecular Formula	C₄H₉NO₂	MS
Molecular Weight	103.12 g/mol	Calculated
Melting Point	197–204°C (with decomposition)	DSC
Solubility	130g/100mL water (25°C)	USP <1236>
pH Stability Range	3.0–7.0	pH meter
Bulk Density	0.49–0.65 g/mL	USP <616>
Loss on Drying	≤0.5%	USP <731>

The powder remains structurally intact after pasteurisation and UHT processing. It has excellent hydrophilicity, allowing total dissolving in aqueous environments without sedimentation. Moderate hygroscopicity but requires proper moisture management.

Certificate of Analysis (COA)

Product Name	γ -Amino Butyric acid	Batch number	/
Batch quantity	10000kgs	Country of origin	China

Analysis Item	Specification	Results
Appearance	White or light yellow crystalline powder	Conforms
Odor /Taste	Characteristic	Conforms
Impurity	None visible impurity	Conforms
Particle size	100% Pass 30 mesh	Conforms
Assay	≥ 99%	99.5%
Loss on Drying	≤ 1.0%	0.42%
PH	6.5 - 7.5	6.95
Ash	≤ 0.10%	0.033%
Chloride(Cl)	≤ 0.02%	< 0.02%
Sulfate(SO₄)	≤ 0.04%	< 0.04%
Ammonium salt	≤ 0.02%	< 0.02%
Molysite	≤ 30 mg/kg	< 30 mg/kg
Arsenic	≤ 0.2 mg/kg	< 0.2 mg/kg
Lead	≤ 0.3 mg/kg	< 0.3 mg/kg
Mercury	≤ 0.1mg/kg	< 0.1mg/kg
Cadmium	≤ 1mg/kg	< 1mg/kg
Total Plate Count	≤ 1000cfu/g	< 10cfu/g
Mould & Yeast	≤ 50cfu/g	< 10cfu/g
E.Coli.	≤ 10cfu/g	< 10cfu/g
Salmonella	Negative/25g	Conforms
Staphylococcus aureus	Negative/25g	Conforms
Storage:	Store in a well-closed container away from moisture,light, oxygen.
Shelf life:	24 months under the conditions above and in its original packaging.

Industrial Applications and Formulation Benefits

Gaba γ-Amino Butyric Acid Powder serves three high-performance sectors:

1. Advanced Nutraceutical Formulations

You may add this powder to sleep support capsules and mood balancing pills. It is stable at high pressure tabletting (up to 20 kN compression force) with no degradation. Synergistic (comes with soothing effects) & coupled with L-theanine & magnesium glycinate. It is compatible with enteric coatings and time-release matrices, which is appreciated by formulators.

2. Functional Beverage Systems

The powder was shown to be entirely soluble in low pH (3.0–4.5) settings in ready to drink stress-relief drinks. It has excellent clarity retention with a shelf life of 18 months at room temperature. It has a neutral organoleptic character and needs less flavour masking than other competing amino acids.

3. Speciality Food Applications

This substance is used by food engineers in functional yoghurts and “calming” confections. Stable throughout fermentation procedures (4 °C, 12–48 h) and chocolate tempering (up to 45 °C) with no loss of bioactivity. Heat resistance allows the creation of novel products in complicated lipidic matrices.

γ-Amino Butyric Acid Powder

Excellence in Manufacturing Process

For our manufacturing we use a regulated biological fermentation pathway:

Step 1: Strain Cultivation

We use unique strains of Lactobacillus selected for their production of the enzyme glutamate decarboxylase (GAD). Fermentation is carried out in 5000L bioreactors under stringent anaerobic conditions.

Step 2: Enzyme Conversion

GAD catalyses the decarboxylation of pharmaceutical grade L-glutamate to GABA. Inline HPLC continually monitors the reaction parameters so that it may get >98% conversion efficiency.

Step 3: Cleanse

Sequential microfiltration (0.2μm) and ultrafiltration (10 kDa MWCO) eliminate cell debris and macromolecular contaminants. Nanofiltration concentrates the GABA solution to optimum levels.

Step 4: Crystallising and Drying

High purity crystals are obtained via crystallisation at regulated temperature. Vacuum drying at 50 °C retains thermosensitive bioactivity and reduces moisture content to 0.5%.

This method removes synthetic residues and provides a homogeneous particle size distribution (D50: 80–120 μm) for improved flowability during encapsulation.

Qualité Certifications

Our extensive certification portfolio improves your formulations:

Quality Management System ISO 9001

Our manufacturing plant adheres to rigorous ISO 9001:2015 standards, guaranteeing constant quality from raw material input to final packaging. Third parties do annual audits to ensure compliance with global quality standards.

HALAL Certified

All batches of Gaba γ-Amino Butyric Acid Powder are verified by recognised Halal authorities to comply with Islamic dietary standards. This accreditation exposes markets throughout the Middle East and South East Asia.

STAR-K Kosher Certification

Our manufacturing line is strictly Kosher, under the supervision of the STAR-K Kosher Certification. This helps you to cater to observant Jewish communities and health-conscious customers who choose verified ingredients.

FDA Registration

We are registered with the U.S. Food and Drug Administration which shows our dedication to North American regulatory compliance and makes the importation process easier for your company.

Qualité Certifications

Flexible Packaging Options

We offer scalable packaging to match your business stage:

Package Type	Quantity	Best For
Food-grade plastic + aluminum foil bag	100g	Laboratory testing and R&D sampling
Food-grade plastic + aluminum foil bag	1kg	Trial production runs
Food-grade plastic + aluminum foil bag	5kg	Medium-scale manufacturing
Food-grade plastic + aluminum foil bag	10kg	Bulk trial orders
Fiber drum with double PE liner	25kg	Commercial production (MOQ)

All packaging materials comply with FDA food contact regulations and EU Regulation 10/2011. Nitrogen flushing and heat sealing protect the powder from moisture and oxidation during transit.

Flexible Packaging Options

Global Transportation Methods

We ensure safe delivery through multiple logistics channels:

Express Courier Services

For sample orders (100g–5kg), we ship via DHL, FedEx, UPS, or EMS. Typical delivery time to North America and Europe is 5–7 business days with full tracking capability.

Air Cargo

Commercial shipments (25kg – 500kg) are sent by air freight with temperature regulated handling. This strategy fits the needs of consumers that want fast re-stocking or to launch time-sensitive product promotions.

Cargo, sea

Sea freight is a cost-effective option for large-volume shipments (>1,000kg). We arrange 20ft or 40ft container shipments with full paperwork for customs clearance.

All packaging is IATA compliant for air transit and IMDG compliant for maritime transportation. We provide business invoices, packing lists, certificates of origin and sanitary certifications as needed by your destination country.

Global Transportation Methods

Warehouse & Shipping

Our Teams

Exhibitions

Frequently Asked Questions

Q: What purity can you guarantee?

A: Our standard purity is ≥99.0% determined by HPLC. Each batch is supplied with a Certificate of Analysis with precise test findings.

Q: How quickly can you ship sample orders?

A: We have stock and samples normally sent within 24 hours after purchase confirmation by fast courier. 100g-1kg.

Q: Is this product suitable for vegan formulations?

A: Yes, we utilise solely plant-based substrates in our fermentation process. It is free from animal components and may be used in vegan and vegetarian applications.

Q: What is the minimum order quantity?

A: We accept sample orders from 100g and above. Our commercial MOQ is 25kg, however we can do trial amounts of 1kg, 5kg or 10kg.

Q: Do you give technical help for formulation development?

A: Yes. Our R&D team is at your disposal to advise you on dose recommendations, stability testing and compatibility with other compounds in your product.

Q: Do you have bespoke specifications?

A: Yes, we are able to offer OEM/ODM services to fulfil your unique needs, such as bespoke purity levels, particle size adjustments and private-label packaging.

Contact Us

Ready to enhance your product line with premium Gaba γ-Amino Butyric Acid Powder? Contact us at sales@nuoyuanbio.com for quotations, samples, or technical inquiries.